This is not the place to sit if you're afraid of heights. Looking left, there was a huge dropoff to the lower level since there were no seats to our left.
I also didn't like that the rows were so wide with what seemed like an infinite amount of seats. If you or someone in your row has an overactive bladder, that could become a problem if you get stuck with tickets in the middle of the row.

You won't be able to see the Gateway Arch and downtown St. Louis at all from these seats since it's in the outfield, FYI.
The back drop is part of what makes Busch Stadium so recognizable and iconic; just like the Pirates' ballpark in Pittsburgh. Also, takes a while to get to these seats once entering the stadium. I would suggest taking the Gate 4 entrance and riding the escalator up.
If you enjoy listening to KMOX 1120, bring your Ipod to the game and listen to their coverage; sitting so high up will leave a lot of fans out of the loop in my opinion.