I haven't been back to Reliant Stadium in a while. I was last there for the Miami Dolphins game in 2012 which was the home opener that year. Was in 347 and I remember being able to see everything really well although it was a 2nd level corner section. They called our area the Mezzanine. The club seats were to the right of us in the next section over so there isn't much of a difference between those and the mezzanine unless you sit along the club sidelines near the 50 yard line.
They hadn't installed the 2 giant jumbo trons at that time so I'm sure the experience has improved. The fans were great too, plenty of Dolphins fans in attendance but they weren't catching too much flak from Texans fans. Texans fans are a generally very well behaved bunch and they love to tailgate. Some of Texas' best BBQ can be found in the Yellow and Blue Lots every Sunday.